ASCB Cell Dance 2012 Winner

Overview of Drosophila Dorsal Closure

During dorsal closure lateral epidermal cells produce filopodia and lamellipodia along their leading edge

Overexpression of Enabled produces ectopic filopodia

Enabled localizes to the tips of filopodial protrusions

Overexpression of Diaphanous produces different ectopic filopodia

During dorsal closure the central amnioserosa cells produce filopodia too